Evaluation of tumor aggressiveness in breast carcinoma according to a scoring method
| Autor: | Augusto Podesta, Mario Wernicke |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Scoring system Paget's Disease Mammary Breast Neoplasms Lymph node metastasis Gastroenterology Metastasis Internal medicine medicine Humans Neoplasm Invasiveness In patient Neoplasm Metastasis Nuclear grade Aged business.industry Nodal metastasis General Medicine Middle Aged Prognosis medicine.disease Carcinoma Papillary Carcinoma Intraductal Noninfiltrating Female Surgery Breast carcinoma business |
| Zdroj: | Journal of Surgical Oncology. 21:107-113 |
| ISSN: | 1096-9098 0022-4790 |
| DOI: | 10.1002/jso.2930210209 |
| Popis: | A scoring system was used to classify 310 patients with breast carcinoma. Tumors were divided and scored according to their architectural patterns and histological features of known prognostic significance such as tumor volume, nuclear grade, mitosis, etc. According to the scoring value, tumors were classified as aggressive (A), moderately aggressive (M), and low aggressive (L). Results showed a higher rate of metastasis in patients with A tumors (72%) and M tumors (63%) when compared with L tumors (22%). There were 175 patients with axillary lymph node metastasis. Of these, 101 had A tumors, 91 had recurrences (90%), and 81 died (80%); of the 56 patients with M tumors, 26 had recurrences (46%) and 9 died (16%) (P less than 0.001). None of the 18 cases classified as L recurred (P less than 0.001). There were 135 patients with no nodal metastasis: 39 had A tumors (21 recurrences [54%] and 19 deaths [49%] and 96 had M and L tumors (1 recurrence [1%] and no deaths) (P less than 0.001). |
| Databáze: | OpenAIRE |
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