The effect of tamoxifen on the genital tract

Autor: Susan M. Ascher, Sandra A. Polin
Rok vydání: 2008
Předmět:
Oncology
Cervix Uteri
Review
Endometrium
Endosonography
Medicine
skin and connective tissue diseases
Radiological and Ultrasound Technology
ultrasound
Incidence
General Medicine
Middle Aged
Magnetic Resonance Imaging
medicine.anatomical_structure
Selective estrogen receptor modulator
Chemotherapy
Adjuvant

Chemoprophylaxis
Vagina
Female
Endometrial polyp
endometrial hyperplasia
hormones
hormone substitutes
and hormone antagonists

medicine.drug
MRI
Adult
medicine.medical_specialty
Antineoplastic Agents
Hormonal

Breast Neoplasms
endometrial cystic atrophy
Risk Assessment
Drug Administration Schedule
Breast cancer
Internal medicine
Humans
Radiology
Nuclear Medicine and imaging

Aged
Uterine sarcoma
Dose-Response Relationship
Drug

business.industry
Endometrial cancer
Ovary
medicine.disease
Female Urogenital Diseases
hysterosonography
Tamoxifen
adenomyosis
business
Follow-Up Studies
Zdroj: Cancer Imaging
ISSN: 1470-7330
Popis: Tamoxifen is a selective estrogen receptor modulator (SERM) that is widely used in the treatment of patients with breast cancer and for chemoprophylaxis in high risk women. Tamoxifen results in a spectrum of abnormalities involving the genital tract, the most significant being an increased incidence of endometrial cancer and uterine sarcoma. This article reviews the effects of tamoxifen on the genital tract and the strengths and weaknesses of various imaging modalities for evaluating the endometrium.
Databáze: OpenAIRE