Risk Factors for Dystonia after Selective Dorsal Rhizotomy in Nonwalking Children and Adolescents with Bilateral Spasticity
| Autor: | Petra E. M. van Schie, Agnita Stadhouder, Jules G. Becher, Annemieke I. Buizer, Pim de Graaf, Laura A. van de Pol, Charlotte van 't Westende, Eline A. M. Bolster, R. Jeroen Vermeulen, Rob L. M. Strijers, Pim W.J.R. van Ouwerkerk |
|---|---|
| Přispěvatelé: | Pediatric surgery, Rehabilitation medicine, Amsterdam Movement Sciences - Restoration and Development, Neurology, Orthopedic Surgery and Sports Medicine, AMS - Trauma and Reconstruction, Radiology and nuclear medicine, Klinische Neurowetenschappen, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Med Staf Spec Neurologie (9), Radiology and Nuclear Medicine, AMS - Restoration & Development |
| Rok vydání: | 2017 |
| Předmět: |
Male
030506 rehabilitation Pediatrics medicine.medical_treatment PATHOGENESIS DISEASE MOTOR FUNCTION 0302 clinical medicine Postoperative Complications Risk Factors SDR Child intervention Dystonia OUTCOMES medicine.diagnostic_test spasticity General Medicine Magnetic Resonance Imaging Caregivers Muscle Spasticity Anesthesia Child Preschool Female medicine.symptom 0305 other medical science MRI PALSY CLINICAL ARTICLE medicine.medical_specialty Adolescent CEREBRAL-PALSY Physical examination CLASSIFICATION Cerebral palsy Rhizotomy 03 medical and health sciences Young Adult medicine otorhinolaryngologic diseases Humans Spasticity Retrospective Studies cerebral palsy Chi-Square Distribution business.industry Retrospective cohort study PERFORMANCE medicine.disease nervous system diseases Acquired disorder Pediatrics Perinatology and Child Health EXPERIENCE Neurology (clinical) business FOLLOW-UP 030217 neurology & neurosurgery Congenital disorder |
| Zdroj: | van de Pol, L A, Vermeulen, J R, van 'T Westende, C, van Schie, P E M, Bolster, E A M, van Ouwerkerk, P W J R, Strijers, R L, Becher, J G, Stadhouder, A, de Graaf, P & Buizer, A I 2018, ' Risk Factors for Dystonia after Selective Dorsal Rhizotomy in Nonwalking Children and Adolescents with Bilateral Spasticity ', Neuropediatrics, vol. 49, no. 1, pp. 44-50 . https://doi.org/10.1055/s-0037-1607395 Neuropediatrics, 49(1), 44-50. Hippokrates Verlag GmbH Neuropediatrics, 49(1), 44-50. Georg Thieme Verlag |
| ISSN: | 1439-1899 0174-304X |
| DOI: | 10.1055/s-0037-1607395 |
| Popis: | We recently showed a beneficial effect of selective dorsal rhizotomy (SDR) on daily care and comfort in nonwalking children with severe bilateral spasticity. However, despite careful selection, some patients showed dystonia after the intervention, in which cases caregivers tended to be less satisfied with the result.The aim of this study is to identify risk factors for dystonia after SDR in children and adolescents with severe bilateral spasticity (GMFCS levels IV/V).Clinical and MRI risk factors for dystonia after SDR were studied in our cohort of 24 patients. Patients with clinical evidence of dystonia and brain MRI showing basal ganglia abnormalities were excluded for SDR.Nine of 24 patients (38%) showed some degree of dystonia after SDR. There was a significant association between the cause of spasticity and dystonia after SDR; in six (67%) patients with a congenital disorder, dystonia was present versus three (20%) with an acquired disorder (Chi-squared test: C(1) = 5.23, p = 0.02).This study allows more optimal selection of patients that may benefit from SDR. Patients with an acquired cause of spasticity, when selected carefully on clinical examination and MRI, rarely show dystonia after SDR. However, patients with an underlying congenital disorder have a considerable risk of dystonia after SDR. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|