Loss of Consciousness and Altered Mental State as Predictors of Functional Recovery Within 6 Months Following Mild Traumatic Brain Injury
| Autor: | Haris I. Sair, Kathleen T. Bechtold, Uju Ofoche, Constantine G. Lyketsos, Allen D. Everett, Haijuan Yan, Freshta Akbari, Frederick K. Korley, Hayley Falk, Vani Rao, Matthew E. Peters, Jeannie Marie Sheppard Leoutsakos, Tim Van Meter, Alexandra Vassila, Durga Roy, Anna J. Hall |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Traumatic brain injury media_common.quotation_subject Poison control Behavioral Symptoms Unconsciousness Suicide prevention Occupational safety and health Young Adult 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Injury prevention medicine Humans Prospective Studies Brain Concussion Aged media_common business.industry Human factors and ergonomics Recovery of Function Middle Aged Prognosis Functional recovery medicine.disease Psychiatry and Mental health 030220 oncology & carcinogenesis Female Neurology (clinical) Consciousness business 030217 neurology & neurosurgery |
| Zdroj: | The Journal of Neuropsychiatry and Clinical Neurosciences. 32:132-138 |
| ISSN: | 1545-7222 0895-0172 |
| DOI: | 10.1176/appi.neuropsych.18120379 |
| Popis: | The authors tested the hypothesis that a combination of loss of consciousness (LOC) and altered mental state (AMS) predicts the highest risk of incomplete functional recovery within 6 months after mild traumatic brain injury (mTBI), compared with either condition alone, and that LOC alone is more strongly associated with incomplete recovery, compared with AMS alone.Data were analyzed from 407 patients with mTBI fromA gradient of risk of incomplete functional recovery at 1, 3, and 6 months postinjury was noted, moving from neither LOC nor AMS, to LOC or AMS alone, to both. LOC was associated with incomplete functional recovery at 1 and 3 months (odds ratio=2.17, SE=0.46, p0.001; and odds ratio=1.80, SE=0.40, p=0.008, respectively). AMS was associated with incomplete functional recovery at 1 month only (odds ratio=1.77, SE=0.37 p=0.007). No association was found between AMS and functional recovery in patients with no LOC. Neither LOC nor AMS was predictive of functional recovery at later times.These findings highlight the need to include symptom-focused clinical variables that pertain to the injury itself when assessing who might be at highest risk of incomplete functional recovery post-mTBI. |
| Databáze: | OpenAIRE |
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