The efficacy of chlorhexidine gel in reduction ofStreptococcus mutans andLactobacillus species in patients treated with radiation therapy
| Autor: | Barry C. McBride, Peter Stevenson-Moore, Joel B. Epstein, John J. Spinelli, Heather Merilees |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male Saliva medicine.drug_class Antibiotics Colony Count Microbial Dentistry Dental Caries Xerostomia Pathology and Forensic Medicine Radiotherapy High-Energy Streptococcus mutans Lactobacillus Oral and maxillofacial pathology medicine Humans General Dentistry Aged biology business.industry Chlorhexidine Middle Aged biology.organism_classification medicine.disease Streptococcaceae Head and Neck Neoplasms Female Salivation Risk assessment business medicine.drug |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology. 71:172-178 |
| ISSN: | 0030-4220 |
| DOI: | 10.1016/0030-4220(91)90461-k |
| Popis: | Xerostomia may develop in patients with cancer who receive radiotherapy that includes the salivary glands in the field. These patients are at high risk of rampant dental caries. Streptococcus mutans and Lactobacillus species have been associated with dental caries. Quantitative counts of these organisms demonstrated high caries risk due to streptococci in 66% and due to lactobacilli in 100% of patients studied. Use of chlorhexidine rinse was shown to reduce S. mutans counts 1.1 logs and lactobacilli 1.1 logs. The use of chlorhexidine gel resulted in a reduction of S. mutans 1.2 logs and lactobacilli 2.2 logs. In the subjects using the rinse, caries risk due to streptococci was reduced to low levels in 44% and due to lactobacilli in only one subject, with reduction to moderate risk in one third and no change in risk in the remaining patients. The use of chlorhexidine gel was found to reduce the caries risk associated with streptococci to low levels in all patients, and the risk associated with lactobacilli to low and moderate risk in two thirds of patients. |
| Databáze: | OpenAIRE |
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