Identification and structural elucidation of bioactive compounds from Scirpoides holoschoenus

Autor: Domenic Mittas, Urban Spitaler, Michaela Bertagnoll, Sabine Oettl, Elvira Gille, Stefan Schwaiger, Hermann Stuppner
Rok vydání: 2022
Předmět:
Zdroj: Phytochemistry. 200
ISSN: 1873-3700
Popis: Phytochemical investigations of dichloromethane and methanol extracts of roots and rhizomes of Scirpoides holoschoenus afforded 21 stilbenes, six flavonoids, six ferulic acid derivatives and four diterpenes. Among these constituents, six stilbenes, one flavonoid, one diterpene and two ferulic acid derivatives, represent previously unreported natural products. Structure elucidation was performed by HRESI-MS, NMR, GC-MS, and ECD data evaluation. The monoprenylated flavonoid (sophoraflavanone B) and all isolated stilbene oligomers (trans-scirpusin B, scirpusin A, cassigarol E, cyperusphenol B, cyperusphenol D, passiflorinol A, cyperusphenol A and mesocyperusphenol A) showed strong inhibitory activities on spore germination of two Botrytis cinerea strains isolated from field-infected grape berries and apple fruits compared to the reference controls resveratrol, piceid, and fenhexamid at a test concentration of 2.0 mM. For sophoraflavanone B and cyperusphenol A, the EC
Databáze: OpenAIRE