The B cell antigen CD75 is a cell surface sialytransferase
| Autor: | Arne Deggerdal, Ivan Stamenkovic, Heidi Kiil Blomhoff, Erlend B. Smeland, Steinar Funderud, Hans Christian Åsheim |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Glycosylation
Sialyltransferase Immunology Cell Antigen presentation Molecular Sequence Data Biology Transfection Cell Line symbols.namesake Antigen medicine Immunology and Allergy Animals Humans Amino Acid Sequence RNA Neoplasm Peptide sequence Gene Library B-Lymphocytes Base Sequence DNA Neoplasm Articles Golgi apparatus Molecular biology Burkitt Lymphoma Sialyltransferases medicine.anatomical_structure Cell culture symbols biology.protein Intracellular |
| Zdroj: | The Journal of Experimental Medicine |
| ISSN: | 0022-1007 |
| Popis: | In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human alpha 2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialytransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events. |
| Databáze: | OpenAIRE |
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