Life of neutrophil: From stem cell to neutrophil extracellular trap
| Autor: | Michal Przemyslaw Pruchniak, Magdalena Arazna, Urszula Demkow |
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| Rok vydání: | 2013 |
| Předmět: |
Pulmonary and Respiratory Medicine
Innate immune system Neutrophils Physiology Effector General Neuroscience Chemotaxis Neutrophil extracellular traps Biology Hematopoietic Stem Cells Granulopoiesis Immunity Innate Neutrophil Activation Cell biology Immunity Immunology Animals Humans Stem cell Extracellular Space Homeostasis |
| Zdroj: | Respiratory Physiology & Neurobiology. 187:68-73 |
| ISSN: | 1569-9048 |
| DOI: | 10.1016/j.resp.2013.02.023 |
| Popis: | Neutrophils are one of the main types of effector cells in the innate immune system. Neutrophils play a major role in fighting diseases and are recruited almost immediately to sites of infection. The neutrophils have a variety of defensive mechanisms and their high affinity to chemotactic agents makes them ideal in the defense against pathogens. New functions of neutrophils have been discovered over the years. The latest role of neutrophils is neutrophil traps, which are a new component of innate anti-microbial immunity. Before neutrophils can effectively kill microorganisms they undergo a series of complex developmental processes. |
| Databáze: | OpenAIRE |
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