Lower urinary tract symptoms and bladder control in advanced Parkinson's disease: Effects of deep brain stimulation in the subthalamic nucleus
| Autor: | Hans Stimpel, Kristian Winge, Lene Werdelin, Steen Rusborg Jensen, Annemette Løkkegaard, Kurt Krøyer Nielsen |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Urologic Diseases medicine.medical_specialty Deep brain stimulation Parkinson's disease Deep Brain Stimulation medicine.medical_treatment Urology urologic and male genital diseases Severity of Illness Index Central nervous system disease Subthalamic Nucleus Lower urinary tract symptoms Surveys and Questionnaires medicine Humans Prospective Studies Aged Urinary bladder Urinary Bladder Overactive business.industry Parkinson Disease Middle Aged medicine.disease Electrodes Implanted Surgery Urinary Bladder Neck Obstruction Urodynamics Subthalamic nucleus medicine.anatomical_structure Neurology Overactive bladder Female International Prostate Symptom Score Neurology (clinical) business |
| Zdroj: | Movement Disorders. 22:220-225 |
| ISSN: | 1531-8257 0885-3185 |
| Popis: | Deep brain stimulation in the subthalamic nucleus (STN) leads to significant improvement in motor function in patients with advanced Parkinson's disease (PD). In this prospective study including 16 patients with PD, we investigated (1) lower urinary tract symptoms (LUTS) by questionnaires International Prostate Symptom Score (IPSS, symptoms only) and Danish Prostate Symptom Score (DanPSS, symptoms and bother of symptoms) and (2) bladder control (assessed by urodynamics) before and after implantation of electrodes in the STN. PD symptoms (Unified Parkinson's Disease Rating Scale score) improved significantly (P < 0.0001), and symptoms of overactive bladder (IPSS) decreased along with the troublesome symptoms of overactive bladder (DanPSS; P < 0.01 for both). Urodynamic parameters before and after implantation of electrodes in the STN, evaluated with and without the stimulation on, did not change significantly. |
| Databáze: | OpenAIRE |
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