Differentiated thyroid cancer in childhood: a literature update
| Autor: | Barbara Vlassopoulou, Olga Karapanou, Marinella Tzanela, Christina Kanaka-Gantenbein |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Oncology
medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Young adolescents 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Thyroid Neoplasms Risk factor Family history Child Lymph node Thyroid cancer business.industry Mortality rate Clinical course General Medicine medicine.disease Response to treatment medicine.anatomical_structure 030220 oncology & carcinogenesis business |
| Zdroj: | Hormones (Athens, Greece). 16(4) |
| ISSN: | 2520-8721 |
| Popis: | Differentiated thyroid cancer in childhood is rare. Apart from family history, radiation exposure is a major risk factor. Although its clinical course is quite aggressive with higher rates of lymph node and pulmonary metastases as compared to adults, the final outcome tends to be favorable with mortality rates less than 2%. We herein review the clinical picture, genetic background response to treatment and recurrence rates of differentiated thyroid cancer in children and young adolescents are thoroughly reviewed and the main differences with adult differentiated thyroid cancer are highlighted. |
| Databáze: | OpenAIRE |
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