A Cyanobacterial Circadian Timing Mechanism

Autor:	Jayna L. Ditty, Susan S. Golden, Stanly B. Williams
Rok vydání:	2003
Předmět:	Genetics Time Factors Transcription Genetic Mechanism (biology) Circadian clock Protein domain Endogeny Gene Expression Regulation Bacterial Biology Cyanobacteria Bacterial circadian rhythms Circadian Rhythm Cell biology KaiC KaiA Circadian rhythm
Zdroj:	Annual Review of Genetics. 37:513-543
ISSN:	1545-2948 0066-4197
DOI:	10.1146/annurev.genet.37.110801.142716
Popis:	▪ Abstract Cyanobacteria such as Synechococcus elongatus PCC 7942 exhibit 24-h rhythms of gene expression that are controlled by an endogenous circadian clock that is mechanistically distinct from those described for diverse eukaryotes. Genetic and biochemical experiments over the past decade have identified key components of the circadian oscillator, input pathways that synchronize the clock with the daily environment, and output pathways that relay temporal information to downstream genes. The mechanism of the cyanobacterial circadian clock that is emerging is based principally on the assembly and disassembly of a large complex at whose heart are the proteins KaiA, KaiB, and KaiC. Signal transduction pathways that feed into and out of the clock employ protein domains that are similar to those in two-component regulatory systems of bacteria.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb850f604ec44705f53d72585de6389 https://doi.org/10.1146/annurev.genet.37.110801.142716 Zobrazit plný text záznamu Plný text ve formátu PDF