Safety and efficacy of inspiratory muscle training for preventing adverse outcomes in patients at risk of prolonged hospitalisation
Autor: | Caroline Ferreira Guerreiro, Eveline Xavier-Souza, Mansueto Gomes Neto, Mayana de Sá Barreto, Balbino Nepomuceno, Naniane Cidreira Almeida |
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Rok vydání: | 2017 |
Předmět: |
Adult
Male Medicine (miscellaneous) 030204 cardiovascular system & hematology Lower risk Breathing Exercises law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Double-Blind Method law Respiratory muscle medicine Intubation Intratracheal Hospitalisation Humans Pharmacology (medical) 030212 general & internal medicine Hospital Mortality Prospective Studies Mortality Adverse effect Prospective cohort study Functionality lcsh:R5-920 Muscle Weakness business.industry Research Muscle weakness Length of Stay Middle Aged Respiratory Muscles Clinical trial Anesthesia Relative risk Female medicine.symptom business lcsh:Medicine (General) |
Zdroj: | Trials Trials, Vol 18, Iss 1, Pp 1-8 (2017) |
ISSN: | 1745-6215 |
Popis: | Background The early institution of inspiratory muscle training on hospitalised patients with no established respiratory deficits could prevent in-hospital adverse outcomes that are directly or indirectly associated to the loss of respiratory muscle mass inherent to a prolonged hospital stay. The objective of the clinical trial is to assess the impact of inspiratory muscle training on hospital inpatient complications. Methods This is a double-blind randomised controlled trial. Subjects in the intervention group underwent an inspiratory muscle training loaded with 50% maximum inspiratory pressure twice daily for 4 weeks from study enrolment. Patients were randomly assigned to an inspiratory muscle training group or a sham inspiratory muscle training group. All patients received conventional physiotherapy interventions. Baseline and post-intervention respiratory and peripheral muscle strength, functionality (performance of activities of daily living), length of hospital stay, and death were evaluated. Clinical outcomes were assessed until hospital discharge. This study was approved by the Institutional Hospital Ethics Committee (03/2014). Results Thirty-one patients assigned to the inspiratory muscle training group and 34 to the sham inspiratory muscle training group were analysed. Patients in the inspiratory muscle training group had a shorter mean length of hospital stay (35.3 ± 2.7 vs. 41.8 ± 3.5 days, p |
Databáze: | OpenAIRE |
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