Chronological changes in skeletal muscle mass following living‐donor liver transplantation: An analysis of the predictive factors for long‐term post‐transplant low muscularity
| Autor: | Nariman Sadykov, Umberto Baccarani, Shinichiro Ono, Takashi Hamada, Masaaki Hidaka, Takanobu Hara, Tomohiko Adachi, Akihiko Soyama, Mitsuhisa Takatsuki, Riccardo Pravisani, Andrea Risaliti, Miriam Isola, Susumu Eguchi |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Multivariate analysis medicine.medical_treatment living-donor liver transplantation Liver transplantation biliary complications Gastroenterology law.invention sarcopenia Young Adult Postoperative Complications Risk Factors law Internal medicine Living Donors medicine Humans Muscle Skeletal Aged Transplantation skeletal muscle mass index business.industry Liver Diseases Skeletal muscle Middle Aged Hepatology Prognosis medicine.disease Skeletal muscle mass Intensive care unit Liver Transplantation medicine.anatomical_structure Sarcopenia Female Living donor liver transplantation business Follow-Up Studies |
| Zdroj: | Clinical Transplantation. 33:e13495 |
| ISSN: | 1399-0012 0902-0063 |
| DOI: | 10.1111/ctr.13495 |
| Popis: | AIM Sarcopenia is associated with high morbidity and mortality before and after liver transplantation (LT). The aim of the study was to evaluate the chronological changes in skeletal muscle mass (SMM) at different time points post-LT and to identify the risk factors for long-term low SMM. METHODS The skeletal muscle index at L3 level (L3-SMI) was used for muscle mass measurement, and the recommended cutoff values of the Japanese Society of Hepatology guidelines were used as criteria for defining low muscularity. RESULTS Preoperative low SMM was recognized in 35.1% of cases. At 1 year after LDLT, 28.9% of patients showed low SMM, without any significant prevalence change in comparison with the preoperative phase (35.1%) or 1 month post-LT (30.7%). Post-LT intensive care unit (ICU) length of stay (OR 1.14, P = 0.03), biliary complications (OR 5.88, P = 0.02), pre-LT low SMM (OR 3.36, P = 0.05), and 1 month post-LT low SMM (OR 10.16, P |
| Databáze: | OpenAIRE |
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