Carriage of an ACME II Variant May Have Contributed to Methicillin-Resistant Staphylococcus aureus Sequence Type 239-Like Strain Replacement in Liverpool Hospital, Sydney, Australia
| Autor: | Mark E. Cooper, David L. Paterson, Sean M. Grimmond, Jason A. Steen, Slade O. Jensen, Thelma Barbagiannakos, Iain B Gosbell, Björn A. Espedido, Joanne L. Mercer, S. J. van Hal |
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| Rok vydání: | 2012 |
| Předmět: |
Methicillin-Resistant Staphylococcus aureus
Pharmacology Strain (chemistry) SCCmec Australia Virulence Biology medicine.disease_cause Polymerase Chain Reaction Methicillin-resistant Staphylococcus aureus Virology Hospitals Electrophoresis Gel Pulsed-Field Epidemiology and Surveillance law.invention Microbiology Infectious Diseases Carriage Bacterial Proteins law Staphylococcus aureus Arginine catabolic mobile element medicine Pharmacology (medical) Polymerase chain reaction |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 56:3380-3383 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.00013-12 |
| Popis: | Approximately 39% of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 239 (ST239)-like bloodstream isolates from Liverpool Hospital (obtained between 1997 and 2008) carry an arginine catabolic mobile element (ACME). Whole-genome sequencing revealed that an ACME II variant is located between orfX and SCC mec III, and based on pulsed-field gel electrophoresis patterns and temporal relationships of all ST239-like isolates ( n = 360), ACME carriage may have contributed to subpulsotype strain replacement. |
| Databáze: | OpenAIRE |
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