Circadian disruption of ICU patients: A review of pathways, expression, and interventions

Autor: Theodoros Katsoulas, Nadia Kavrochorianou, Olav Muurlink, George Baltopoulos, George Fildissis, Anna Korompeli
Rok vydání: 2016
Předmět:
Zdroj: Journal of critical care. 38
ISSN: 1557-8615
Popis: Intensive care unit patients typically exhibit pathologic wakefulness, poor quality of daytime sleep, nocturnal sleep fragmentation, and sleep patterns that feature the absence of slow wave sleep and rapid eye movement. This article offers a review of the existing literature examining circadian desynchronization in critically ill patients, highlighting contributing factors identified by scholars, and circadian abnormalities observed in these patients. It discusses potential implications for clinical practice and suggests avenues of future research. Elucidating the role of circadian rhythms in the management of critical illness can guide future chronotherapeutic approaches and optimize patient outcomes.
Databáze: OpenAIRE