| Popis: |
Additional file 1: Figure S1. Histogram distribution of peptide length. Figure S2. Unique cellular component origins of proteins. For this analysis, only proteins originating from nucleus, cytosol, mitochondria, and Golgi apparatus were considered. Figure S3. Multiple cellular component origins of peptides. Figure S4. Protein class origins of proteins. For this analysis, only categories present in CTL vs RT were considered for CTL vs NBTXR3+RT. Figure S5. Extracellular ATP analysis for (A) HCT116, (B) 42-MG-BA and (C) PANC-1 cells. HMGB1 release measurement for (D) HCT116, (E) 42-MG-BA and (F) PANC-1 cells. Presented data were obtained from at least two independent experiments (n≥2). Data are represented as mean fold increase ± SEM compared to unirradiated control cells. Table S1. List of peptides and accession number of corresponding proteins. Table S2. NBTXR3 concentration (µM), irradiation dose (Gy), irradiation source and number of individual experiments for each cell line and each DAMP. |
