Liberal Versus Restrictive Hemoglobin Levels as Thresholds for Blood Transfusions
| Autor: | Allan B. Wolfson, John Z. Hillenkamp |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Blood transfusion
business.industry Anemia medicine.medical_treatment Volume overload Length of hospitalization 030208 emergency & critical care medicine General Medicine Hemoglobin levels medicine.disease Hemoglobins 03 medical and health sciences 0302 clinical medicine Chronic disease Anesthesia Emergency Medicine medicine Oxygen delivery Humans Blood Transfusion Myocardial infarction Erythrocyte Transfusion business |
| Zdroj: | Academic Emergency Medicine. 28:593-594 |
| ISSN: | 1553-2712 1069-6563 |
| DOI: | 10.1111/acem.14153 |
| Popis: | Blood transfusion is a common treatment of anemia due to chronic disease or acute blood loss. However, there continues to be uncertainty concerning the appropriate threshold for transfusion. A restrictive protocol could decrease blood administered, transmissible infections, transfusion reactions, volume overload, and utilization of a limited commodity. However, anemia may result in decreased oxygen delivery which could lead to metabolic dysfunction an increased cell death. Determining an appropriate transfusion threshold is thus an important objective. A previous Cochrane review found the use of restrictive thresholds decreased transfusions compared to liberal thresholds. No difference in secondary outcomes, including 30-day mortality, hospital length of stay, cardiac events, and myocardial infarction, was noted. |
| Databáze: | OpenAIRE |
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