Severe mitral regurgitation--relations between magnetic resonance imaging, echocardiography and natriuretic peptides

Autor:	Johan Landelius, Mats Stridsberg, Elisabeth Ståhle, Tomas Bjerner, Laila Hellgren, Per Kvidal
Rok vydání:	2008
Předmět:	Adult Male medicine.medical_specialty medicine.drug_class Heart Ventricles Regurgitation (circulation) Severity of Illness Index Predictive Value of Tests Internal medicine Natriuretic Peptide Brain Severity of illness Natriuretic peptide Humans Medicine Heart Atria cardiovascular diseases Aorta Aged Mitral regurgitation Vena contracta medicine.diagnostic_test business.industry Mitral Valve Insufficiency Reproducibility of Results Magnetic resonance imaging Middle Aged Magnetic Resonance Imaging Echocardiography Doppler Peptide Fragments Research Design Predictive value of tests Regurgitant fraction Cardiology Female Radiology Cardiology and Cardiovascular Medicine business Atrial Natriuretic Factor Biomarkers
Zdroj:	Scandinavian Cardiovascular Journal. 42:48-55
ISSN:	1651-2006 1401-7431
DOI:	10.1080/14017430701678691
Popis:	Assessment of the severity of mitral regurgitation by echocardiography can be technically demanding in certain patients and supplementary methods are therefore desirable. This study addressed the agreement between magnetic resonance imaging (MRI) and echocardiography, and their relations to natriuretic peptides (NT-proANP and NT-proBNP), in quantifying severe mitral regurgitation.Eighteen patients with severe mitral regurgitation scheduled for surgery underwent MRI, echocardiography and assay of natriuretic peptides preoperatively for clinical assessment.MRI and echocardiography were comparable in measuring severity of regurgitation qualitatively but not quantitatively, mitral regurgitant fraction (mean difference 27.5 (11) ml). There was a correlation between increasing regurgitant fraction on MRI and increased levels of plasma NT-proANP and NT-proBNP. In echocardiography, increasing vena contracta width and increasing PISA correlated to increased levels of plasma NT-proANP and NT-proBNP. No other correlation was found between measures on MRI and echocardiography and natriuretic peptides.MRI and echocardiography were comparable grading the severity of mitral regurgitation with qualitative measures but not with quantitative measures. MRI might be a complement to echocardiography when a more distinct measure of the regurgitant volume is needed, as in paravalvular leakage.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e86d3a3584f3fc28a62662e44f9da9d https://doi.org/10.1080/14017430701678691 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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