The inhibitory effect of radix salviae miltiorrhizae on hypoxic structural remodeling of intra-acinar pulmonary arteries
Autor: | Xi Si-chuan, Zhang Wan-rong, Che Dongyuan |
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Rok vydání: | 1994 |
Předmět: |
Plant Extracts
business.industry Salvia miltiorrhiza Pulmonary Artery Pharmacology Hypoxia (medical) Structural remodeling medicine.disease Pulmonary hypertension Muscle Smooth Vascular Rats Rats Sprague-Dawley Endothelial stem cell Management of Technology and Innovation Medicine public health Anesthesia Animals Medicine Endothelium Vascular medicine.symptom Hypoxia business Inhibitory effect Drugs Chinese Herbal |
Zdroj: | Journal of Tongji Medical University. 14:148-152 |
ISSN: | 0257-716X |
DOI: | 10.1007/bf02886795 |
Popis: | The inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on hypoxic structural remodeling of intra-acinar pulmonary arteries (IAPA) was observed by light and electron microscopy and morphometry. It was found that RSM can not only dilate IAPA and relieve the hypoxic injuries to endothelia cells, but also inhibit the active muscularization of IAPA in the hypoxic animals, suggesting that RSM plays a very important role in inhibiting structural remodeling of IAPA and pulmonary hypertension. |
Databáze: | OpenAIRE |
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