Surgical impact on serum anti-Müllerian hormone in women with benign ovarian cyst: A prospective study

Autor: Jeong Ho Rhee, Joon Cheol Park, Won Kyu Jang, Su Yeon Lim, Anna Lee, Kyung Ryul Lee
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Obstetrics & Gynecology Science
ISSN: 2287-8580
2287-8572
Popis: OBJECTIVE The aim of this study was to evaluate the surgical impact of benign ovarian mass on ovarian reserve as measured by serum follicle stimulating hormone (FSH), estradiol (E2) and anti-Mullerian hormone (AMH) levels, antral follicle count (AFC) and ovarian volumes. In addition, the differences in ovarian reserve impairment between endometrioma cystectomy and non-endometrioma cystectomy were investigated. METHODS In this prospective study, 22 patients of reproductive age (range, 18.35 years) with benign ovarian masses were enrolled to undergo laparoscopic cystectomy. Of whom 12 had endometriomas and 10 had non-endometriomas. On early follicular phase (day 3) of the cycle preceding the operation and three months after the laparoscopic cystectomy, serum levels of FSH, E2 and AMH, AFC and ovarian volumes were measured in all patients. Data were analyzed with Mann-Whitney U-test and Wilcoxon rank test using SPSS ver. 12.0 for statistic analysis. RESULTS Median level of serum AMH was significantly decreased from 5.48 ng/mL (interquartile range [IQR], 2.80-7.47) before cystectomy to 2.56 ng/mL (IQR, 1.74-4.32) 3 months postoperation (P
Databáze: OpenAIRE