Molecular Survey of Zoonotic Agents in Rodents and Other Small Mammals in Croatia
| Autor: | W. Ian Lipkin, Josipa Habuš, Rafal Tokarz, Josip Margaletić, Petra Svoboda, Komal Jain, Marko Vucelja, Nenad Turk, Alemka Markotić, Ante Tadin, Aaloki Desai |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Bartonella Apodemus agrarius Croatia animal diseases Leptospira Borrelia miyamotoi Borrelia afzelii Babesia microti Ehrlichia Anaplasma F. tularensis hantavirus orthopoxvirus 030231 tropical medicine 030106 microbiology Rodentia medicine.disease_cause Microbiology 03 medical and health sciences 0302 clinical medicine Zoonoses Virology Borrelia parasitic diseases medicine Animals Protozoan Infections Animal Phylogeny Francisella tularensis Bacteria biology virus diseases Bacterial Infections Articles bacterial infections and mycoses biology.organism_classification Infectious Diseases bacteria Parasitology |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 94:466-473 |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | Croatia is a focus for many rodent-borne zoonosis. Here, we report a survey of 242 rodents and small mammals, including 43 Myodes glareolus, 131 Apodemus flavicollis, 53 Apodemus agrarius, three Apodemus sylvaticus, six Sorex araneus, four Microtus arvalis, one Microtus agrestis, and one Muscardinus avellanarius, collected at eight sites in Croatia over an 8-year period. Multiplex MassTag polymerase chain reaction (PCR) was used for detection of Borrelia, Rickettsia, Bartonella, Babesia, Ehrlichia, Anaplasma, Francisella tularensis, and Coxiella burnetii. Individual PCR assays were used for detection of Leptospira, lymphocytic choriomeningitis virus, orthopoxviruses, flaviviruses, hantaviruses, and Toxoplasma gondii. Of the rodents, 52 (21.5%) were infected with Leptospira, 9 (3.7%) with Borrelia miyamotoi, 5 (2%) with Borrelia afzelii, 29 (12.0%) with Bartonella, 8 (3.3%) with Babesia microti, 2 (0.8%) with Ehrlichia, 4 (1.7%) with Anaplasma, 2 (0.8%) with F. tularensis, 43 (17.8%) with hantaviruses, and 1 (0.4%) with an orthopoxvirus. Other agents were not detected. Multiple infections were found in 32 rodents (13.2%): dual infections in 26 rodents (10.7%), triple infections in four rodents (2.9%), and quadruple infections in two rodents (0.8%). Our findings indicate that rodents in Croatia harbor a wide range of bacteria and viruses that are pathogenic to humans. |
| Databáze: | OpenAIRE |
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