Permanent Bilateral Carotid Filters for Stroke Prevention in Atrial Fibrillation
| Autor: | Petr Neuzil, Vivek Y. Reddy, Roland Veltkamp, Guy Shinar, Ofer Yodfat, Avraham Neta, Tom de Potter, Stuart J. Connolly |
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| Přispěvatelé: | St Marys Development Trust, Commission of the European Communities |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Percutaneous Carotid Artery Common Carotid filter Common carotid artery law.invention Invasive Electrophysiology and Pacing (E. Kevin Heist Section Editor) Randomized controlled trial law Embolic protection Internal medicine medicine.artery Stroke prevention medicine Animals Humans 1102 Cardiorespiratory Medicine and Haematology Sheep business.industry Atrial fibrillation Prostheses and Implants medicine.disease Stroke Treatment Outcome Cardiovascular System & Hematology Filter (video) Cardiology Observational study Implant Cardiology and Cardiovascular Medicine business |
| Zdroj: | Current Cardiology Reports |
| ISSN: | 1534-3170 1523-3782 |
| Popis: | Purpose of Review A novel permanent carotid filter device for percutaneous implantation was developed for the purpose of stroke prevention. In this review, we cover rationale, existing preclinical and clinical data, and potential future directions for research using such a device. Recent Findings The Vine™ filter was assessed for safety in sheep and in 2 observational human studies, the completed CAPTURE 1 (n = 25) and the ongoing CAPTURE 2 (planned n = 100). CAPTURE 1 has shown high procedural and long-term implant safety. A control group was not available for comparison. Summary A mechanical filter for permanent stroke prevention can be implanted bilaterally in the common carotid artery safely and efficiently. A randomized trial is planned for 2021 (n = 3500, INTERCEPT) to demonstrate superiority of a filter + anticoagulation strategy over anticoagulation alone in patients at high risk for ischemic stroke. |
| Databáze: | OpenAIRE |
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