Clinical, Angiographic Characteristics and In-Hospital Outcomes of Smoker and Nonsmoker Patients After Primary Percutaneous Coronary Intervention
| Autor: | Tariq Ashraf, Abdul Samad Achakzai, Rashid Aziz, Tahir Saghir, Syed Ishtiaq Rasool, Syed Muhammad Afaque, Syed Nadeem Hassan Rizvi, Alizay Lateef, Muhammad Nauman Khan, Musa Karim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Epidemiology medicine.medical_treatment Disease 030204 cardiovascular system & hematology Coronary Angiography Cigarette Smoking Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Internal medicine Diabetes mellitus medicine Humans Pakistan 030212 general & internal medicine Myocardial infarction Prospective Studies Prospective cohort study Aged Retrospective Studies Community and Home Care Aged 80 and over Smokers business.industry Percutaneous coronary intervention Retrospective cohort study Non-Smokers Middle Aged medicine.disease Hospital outcomes behavior and behavior mechanisms Smoking cessation ST Elevation Myocardial Infarction Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Global Heart; Vol 14, No 3 (2019); 335-341 |
| ISSN: | 2211-8179 2211-8160 |
| Popis: | Smoking is a well-established cardiac risk factor there is dearth of Local data regarding clinical and angiographic characteristics of smoker patients.This study was planned to assess the differences in the clinical characteristics, angiographic characteristics, and in-hospital outcomes of smokers and nonsmokers after primary percutaneous coronary intervention at a tertiary care hospital in Karachi, Pakistan.We included patients between 40 and 80 years of age diagnosed with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention from July 1, 2017, to March 31, 2018. Clinical and angiographic characteristics and in-hospital outcomes were obtained from the cases submitted to the National Cardiovascular Data Registry's CathPCI (Catheterization-Percutaneous Coronary Intervention) Registry from our site.A total of 3,255 patients were included in this study. Smokers consist of 25.1% (817) of the total sample. A high majority of smokers were male, 98.8% (807), and smokers were relatively younger as compared to nonsmokers with a mean age of 52.89 ± 10.59 versus 55.98 ± 11.24 years; p0.001. Smokers had higher post-procedure TIMI (Thrombolysis In Myocardial Infarction) flow grade III: 97.8% (794) versus 95.53% (2,329); p = 0.037, and they had a relatively low mortality rate: 2.69% (22) versus 3.16% (77); p = 0.502.Smokers were predominantly male and around 3 years younger than nonsmokers. Diabetes mellitus and hypertension were less common among smokers and single-vessel disease was the more common angiographic finding for smokers as compared to 3-vessel disease for nonsmokers. No statistically significant differences in in-hospital outcomes were observed. ST-segment elevation myocardial infarction in smokers despite younger age and the low atherosclerotic risk profile, in our region, emphasize the need for nicotine addiction management and smoking cessation campaigns at large and for pre-discharge counseling. |
| Databáze: | OpenAIRE |
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