Orbital Pseudotumor: Uncommon Initial Presentation of IgG4-Related Disease
| Autor: | Luis Otávio Cardoso Mocarzel, Beatriz Nayra Dias de Andrade, Teresa Rachel Junqueira Carbone, Pedro Gemal Lanzieri, Ricardo Azêdo de Luca Montes |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Lymphocytic infiltration lcsh:Diseases of the musculoskeletal system medicine.diagnostic_test Orbital pseudotumor integumentary system business.industry fungi Case Report General Medicine Disease medicine.disease Elevated serum Tissue fibrosis Biopsy parasitic diseases medicine IgG4-related disease Presentation (obstetrics) lcsh:RC925-935 business skin and connective tissue diseases |
| Zdroj: | Case Reports in Rheumatology, Vol 2015 (2015) Case Reports in Rheumatology |
| ISSN: | 2090-6897 2090-6889 |
| Popis: | IgG4-related disease (IgG4-RD) encompasses a group of fibroinflammatory conditions recognized in recent times. The main clinical features include variable degrees of tissue fibrosis, tumorlike expansions, perivascular lymphocytic infiltration rich in IgG4-positive plasma cells, and elevated serum IgG4. A case has been reported of an elderly patient with an unexplained unilateral exophthalmia; biopsy was performed and revealed lymphocytic infiltration, suggesting IgG4-RD. High serum levels of IgG4, in association with a good response to steroid therapy and to the exclusion of other diagnoses, confirmed the hypothesis of orbital pseudotumor by IgG4-RD. |
| Databáze: | OpenAIRE |
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