Lateral cephalometric analysis for treatment planning in orthodontics based on MRI compared with radiographs: A feasibility study in children and adolescents

Autor: Tim Hilgenfeld, Sabine Heiland, Sebastian Zingler, Martin Bendszus, Christopher J. Lux, Ann-Kathrin Ozga, Andreas Sommer, Philipp Kickingereder, Eduardo Lazo Gonzalez, Alexander Heil
Rok vydání: 2017
Předmět:
Male
Teeth
Intraclass correlation
Radiography
lcsh:Medicine
Adolescents
Patient Care Planning
Diagnostic Radiology
030218 nuclear medicine & medical imaging
Incisors
0302 clinical medicine
Image Processing
Computer-Assisted
Medicine and Health Sciences
Prospective Studies
Child
lcsh:Science
Tomography
Orthodontics
Multidisciplinary
Anthropometry
medicine.diagnostic_test
Radiology and Imaging
Radiation Exposure
Craniometry
Magnetic Resonance Imaging
In Vivo Imaging
Female
Anatomy
Research Article
Cephalometric analysis
Adolescent
Cephalometry
Imaging Techniques
Oral Medicine
Neuroimaging
Research and Analysis Methods
Imaging phantom
03 medical and health sciences
Imaging
Three-Dimensional
Diagnostic Medicine
medicine
Humans
business.industry
lcsh:R
Biology and Life Sciences
Magnetic resonance imaging
030206 dentistry
Gold standard (test)
Computed Axial Tomography
Jaw
Age Groups
People and Places
Feasibility Studies
Population Groupings
lcsh:Q
Tomography
X-Ray Computed
business
Head
Digestive System
Neuroscience
Zdroj: PLoS ONE, Vol 12, Iss 3, p e0174524 (2017)
PLoS ONE
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0174524
Popis: Objective The objective of this prospective study was to evaluate whether magnetic resonance imaging (MRI) is equivalent to lateral cephalometric radiographs (LCR, “gold standard”) in cephalometric analysis. Methods The applied MRI technique was optimized for short scanning time, high resolution, high contrast and geometric accuracy. Prior to orthodontic treatment, 20 patients (mean age ± SD, 13.95 years ± 5.34) received MRI and LCR. MRI datasets were postprocessed into lateral cephalograms. Cephalometric analysis was performed twice by two independent observers for both modalities with an interval of 4 weeks. Eight bilateral and 10 midsagittal landmarks were identified, and 24 widely used measurements (14 angles, 10 distances) were calculated. Statistical analysis was performed by using intraclass correlation coefficient (ICC), Bland-Altman analysis and two one-sided tests (TOST) within the predefined equivalence margin of ± 2°/mm. Results Geometric accuracy of the MRI technique was confirmed by phantom measurements. Mean intraobserver ICC were 0.977/0.975 for MRI and 0.975/0.961 for LCR. Average interobserver ICC were 0.980 for MRI and 0.929 for LCR. Bland-Altman analysis showed high levels of agreement between the two modalities, bias range (mean ± SD) was -0.66 to 0.61 mm (0.06 ± 0.44) for distances and -1.33 to 1.14° (0.06 ± 0.71) for angles. Except for the interincisal angle (p = 0.17) all measurements were statistically equivalent (p < 0.05). Conclusions This study demonstrates feasibility of orthodontic treatment planning without radiation exposure based on MRI. High-resolution isotropic MRI datasets can be transformed into lateral cephalograms allowing reliable measurements as applied in orthodontic routine with high concordance to the corresponding measurements on LCR.
Databáze: OpenAIRE
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