Failure of heterogeneous amyloid-enhancing factor in geriatric squirrel monkeys (Saimiri boliviensis)

Autor:	Naotaka Ishiguro, Chieko Kai, Takeshi Kuraishi, Kanata Ibi, Tomoaki Murakami, Tokuma Yanai, Shosaku Hattori
Rok vydání:	2014
Předmět:	Male Pathology medicine.medical_specialty Aging Amyloid Pan troglodytes Stimulation AA amyloidosis medicine Animals Serum amyloid A Amyloid enhancing factor Saimiri Glycoproteins General Veterinary biology Amyloidosis medicine.disease biology.organism_classification Saimiri boliviensis Amyloid deposition Animal Science and Zoology Administration Intravenous Cattle Female Chickens
Zdroj:	Journal of medical primatology. 43(6)
ISSN:	1600-0684
Popis:	Background Cross-species transmission of AA amyloidosis between primates and other animals has not been previously reported. Methods Eight geriatric squirrel monkeys were intravenously administered chimpanzee, bovine, or chicken amyloid fibrils and simultaneously received inflammatory stimulation. Results AA amyloid deposition was not detected in any of the monkeys histopathologically or immunohistochemically. Conclusions These results suggest that heterogeneous AA amyloidosis may not be easily transmitted into primates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5c6cea16de18dc0f05c4631de4f61f https://pubmed.ncbi.nlm.nih.gov/25041324 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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