Herbicidins A and B, two new antibiotics with herbicidal activity. II. Fermentation, isolation and physico-chemical characterization
| Autor: | Mamoru Arai, Junko Yabe, Akira Terahara, Hisashi Kayamori, Tatsuo Haneishi |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Pharmacology
Chromatography Chemical Phenomena biology Chemistry Physical Herbicides Chemistry medicine.drug_class Elution Silica gel Antibiotics Purine Nucleosides Adenine nucleoside biology.organism_classification Streptomyces Anti-Bacterial Agents chemistry.chemical_compound Adsorption Solubility Fermentation Drug Discovery medicine Moiety |
| Zdroj: | The Journal of Antibiotics. 29:870-875 |
| ISSN: | 1881-1469 0021-8820 |
| DOI: | 10.7164/antibiotics.29.870 |
| Popis: | Herbicidins were produced in submerged fermentation by Streptomyces sagonomensis. Isolation of the antibiotics from the culture broth was performed by adsorption on resinous adsorbent followed by elution with aqueous acetone. Herbicidins A and B were separated from each other by counter-current distribution on a Ronor column or by silica gel chromatography. Physico-chemical characterization revealed that herbicidins are new antibiotics having an adenine nucleoside moiety in their structures. |
| Databáze: | OpenAIRE |
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