Preexposure Prophylaxis (PrEP) for HIV Prevention: The Primary Care Perspective
| Autor: | James Conniff, Ann Evensen |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Anti-HIV Agents Cost-Benefit Analysis Motivational interviewing Administration Oral HIV Infections Motivational Interviewing Emtricitabine Chemoprevention Risk Assessment Medication Adherence Men who have sex with men 03 medical and health sciences 0302 clinical medicine Pharmacotherapy Unsafe Sex Humans Medicine 030212 general & internal medicine Dosing Homosexuality Male Substance Abuse Intravenous Tenofovir 030505 public health Primary Health Care business.industry Transmission (medicine) Public Health Environmental and Occupational Health Drug Combinations Sexual Partners Family medicine Practice Guidelines as Topic Serodiscordant Female 0305 other medical science Family Practice business medicine.drug |
| Zdroj: | The Journal of the American Board of Family Medicine. 29:143-151 |
| ISSN: | 1558-7118 1557-2625 |
| DOI: | 10.3122/jabfm.2016.01.150223 |
| Popis: | Until recently there have been few primary care office-based strategies to reduce the transmission of HIV. In May 2014 the Centers for Disease Control and Prevention published updated practice guidelines recommending the use of preexposure prophylaxis (PrEP) with daily oral dosing of tenofovir/emtricitabine to help prevent HIV infection in high-risk individuals (strength of recommendation, A). Knowledge of PrEP among primary care providers is low, however, and this intervention is likely reaching only a small fraction of eligible patients. PrEP is recommended for certain injection drug users, nonmonogamous men who have sex with men, heterosexual women who have sex with men who have sex with men or injection drug users, and those in HIV serodiscordant relationships. Providers should obtain baseline laboratory values and provide initial counseling before prescribing PrEP. Regular office visits are necessary to ensure adherence, provide ongoing counseling, and monitor for side effects, including nausea, abdominal pain, headache, and, less commonly, increased creatinine. Guidelines and toolkits have been developed to assist in incorporating PrEP into primary care practice. PrEP is gaining widespread acceptance and has become a crucial tool in the fight to stop the spread of HIV. |
| Databáze: | OpenAIRE |
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