KiSS-1: a likely candidate for the photoperiodic control of reproduction in seasonal breeders
| Autor: | Jens D. Mikkelsen, Paul Pévet, Mireille Masson-Pévet, Michel Saboureau, Florent G. Revel, Valérie Simonneaux |
|---|---|
| Přispěvatelé: | Institut des Neurosciences Cellulaires et Intégratives (INCI), Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Department of Functional Neuroanatomy, NeuroSearch A/S, Challet, Etienne |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
endocrine system Time Factors Physiology media_common.quotation_subject Photoperiod Hypothalamus Zoology Biology Models Biological Pineal Gland Retina Receptors G-Protein-Coupled Melatonin Pineal gland Physiology (medical) Internal medicine Seasonal breeder medicine Animals Humans [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] media_common photoperiodism Neurons Kisspeptins Suprachiasmatic nucleus Reproduction Tumor Suppressor Proteins Gonadotropin secretion medicine.anatomical_structure Endocrinology [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] Seasons hormones hormone substitutes and hormone antagonists medicine.drug Receptors Kisspeptin-1 |
| Zdroj: | Chronobiology International Chronobiology International, Taylor & Francis, 2006, 23(1-2), pp.277-287 |
| ISSN: | 0742-0528 1525-6073 |
| Popis: | In seasonal species, photoperiod exerts tight regulation of reproduction to ensure that birth occurs at the most favorable time of yr. A distinct photoneuroendocrine circuit composed of the retina, suprachiasmatic nucleus (SCN) of the hypothalamus, and pineal gland transduces daylength into a rhythmic secretion of melatonin. The duration of the night-time rise of this hormone conveys daylength information to the organism. Melatonin is known to mediate the control of seasonal reproduction, but how it modulates sexual activity is far from understood. Recent data indicate that the product of the KiSS-1 gene is a potent stimulator of the hypothalamic-pituitary-gonadal axis and may play, together with its receptor GPR54, a central role in the neuroendocrine regulation of gonadotropin secretion. This article briefly reviews these findings and presents arguments that KiSS-1 could take part in the seasonal control of reproduction. |
| Databáze: | OpenAIRE |
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