Associations of cortisol with posttraumatic stress symptoms and negative life events: a study of police officers and firefighters
| Autor: | Henk M. van der Ploeg, Inge Bramsen, Tjabe Smid, Anja C. Huizink, Pauline Slottje, Anke B. Witteveen |
|---|---|
| Přispěvatelé: | EMGO+ - Musculoskeletal Health, EMGO+ - Quality of Care, Developmental Psychopathology (RICDE, FMG), Faculteit der Geneeskunde, Adult Psychiatry, Medical psychology, Public and occupational health, EMGO - Musculoskeletal health, EMGO - Quality of care |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Psychosis medicine.medical_specialty Hypothalamo-Hypophyseal System endocrine system Hydrocortisone Endocrinology Diabetes and Metabolism Poison control Pituitary-Adrenal System Occupational safety and health Disasters Life Change Events Stress Disorders Post-Traumatic Endocrinology SDG 3 - Good Health and Well-being Injury prevention Epidemiology medicine Humans Psychiatry Saliva Biological Psychiatry Endocrine and Autonomic Systems Middle Aged medicine.disease Police Psychiatry and Mental health Female Psychology Developmental Psychopathology Anxiety disorder Glucocorticoid hormones hormone substitutes and hormone antagonists Clinical psychology medicine.drug |
| Zdroj: | Psychoneuroendocrinology, 35, 7, pp. 1113-1118 Psychoneuroendocrinology, 35, 1113-1118 Psychoneuroendocrinology, 35(7), 1113-1118. Elsevier Ltd Witteveen, A B, Huizink, A C, Slottje, P, Bramsen, I, Smid, T & van der Ploeg, H M 2010, ' Associations of cortisol with posttraumatic stress symptoms and negative life events: a study of police officers and firefighters ', Psychoneuroendocrinology, vol. 35, no. 7, pp. 1113-1118 . https://doi.org/10.1016/j.psyneuen.2009.12.013 Psychoneuroendocrinology, 35(7), 1113-1118. Elsevier Psychoneuroendocrinology, 35(7), 1113-1118. Elsevier Limited |
| ISSN: | 1873-3360 0306-4530 |
| Popis: | Contains fulltext : 90661.pdf (Publisher’s version ) (Closed access) Given the inconsistent associations of cortisol with posttraumatic stress disorder (PTSD), analysis of basal functioning of the hypothalamic-pituitary-adrenal (HPA) axis in subjects frequently exposed to trauma and critical incidents with a range of PTSD symptomatology, may be valuable. In an epidemiological sample of 1880 police officers and firefighters, associations of salivary cortisol with PTSD, negative life events (NLE) and exposure to a major air disaster more than 8 years earlier, was explored. Probable PTSD was unrelated to cortisol level while past (>8 years earlier) and more recently experienced NLE were associated with lower cortisol levels even after adjustment for confounders. Disaster exposure interacted significantly with PTSD symptoms on cortisol level. In the disaster-exposed subgroup, PTSD symptomclusters of intrusion and hyperarousal (in particular sleep disturbances), were associated with lower and higher cortisol levels, respectively. A final model using backward elimination strategy, retained time of saliva sampling, smoking, gender, and NLE > 8 years earlier in the total sample, and additionally symptomclusters of intrusion and hyperarousal in the disaster-exposed subgroup. The final model explained 10% of the variance in cortisol. The findings are discussed in relation to literature on posttraumatic stress and basal functioning of the HPA-axis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect