A model of morphogenesis
Autor: | F.W. Cummings |
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Rok vydání: | 2004 |
Předmět: |
Statistics and Probability
Physics Quantitative Biology - Subcellular Processes Quantitative Biology::Molecular Networks Gauss Zero (complex analysis) Wnt signaling pathway Morphogenesis FOS: Physical sciences Pattern formation Geometry Animal development Condensed Matter Physics Gastrulation Coupling (electronics) Classical mechanics Biological Physics (physics.bio-ph) FOS: Biological sciences Physics - Biological Physics Subcellular Processes (q-bio.SC) |
Zdroj: | Physica A: Statistical Mechanics and its Applications. 339:531-547 |
ISSN: | 0378-4371 |
DOI: | 10.1016/j.physa.2004.04.047 |
Popis: | A new suggestion for pattern formation in biological systems is proposed. The interaction of two signaling pathways provides complex patterning. The interaction of two pathways involves few of the biochemical complexities of the pathways. The 'Wnt' pathway is proposed to be one of these, in interaction with others, one at a time, perhaps sequentially, such as Hunchback (Hh), Notch, BMP, etc., those involved in development of metazoa. It is further shown how such interactions can easily lead to such epithelial movements as gastrulation. Numerical simulations of the model are given. 30 pages, 5 figures |
Databáze: | OpenAIRE |
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