A small-scale robotic manipulandum for motor training in stroke rats
| Autor: | Roger Gassert, Lina Graber, René Fluit, Bogdan Vigaru, Maximilian Schubring-Giese, Olivier Lambercy, Pascal Wespe, Andreas R. Luft |
|---|---|
| Přispěvatelé: | University of Zurich, Vigaru, Bogdan |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Engineering medicine.medical_treatment 2207 Control and Systems Engineering 610 Medicine & health Kinematics DC motor Physical medicine and rehabilitation medicine Animals METIS-278279 Dropout (neural networks) Neurorehabilitation Robot kinematics Rehabilitation business.industry 2208 Electrical and Electronic Engineering Stroke Rehabilitation Control engineering Robotics Neurophysiology Rats 10040 Clinic for Neurology body regions 2742 Rehabilitation Robot business Psychomotor Performance |
| Zdroj: | ISSUE=12;TITLE=IEEE 12th International Conference on Rehabilitation Robotics, ICORR 2011 |
| Popis: | The investigation and characterization of sensori-motor learning and execution represents a key objective for the design of optimal rehabilitation therapies following stroke. By supplying new tools to investigate sensorimotor learning and objectively assess recovery, robot assisted techniques have opened new lines of research in neurorehabilitation aiming to complement current clinical strategies. Human studies, however, are limited by the complex logistics, heterogeneous patient populations and large dropout rates. Rat models may provide a substitute to explore the mechanisms underlying these processes in humans with larger and more homogeneous populations. This paper describes the development and evaluation of a three-degrees-of-freedom robotic manipulandum to train and assess precision forelimb movement in rats before and after stroke. The mechanical design is presented based on the requirements of interaction with rat kinematics and kinetics. The characterization of the robot exhibits a compact, low friction device, with a sufficient bandwidth suitable for motor training studies with rodents. The manipulandum was integrated with an existing training environment for rodent experiments and a first study is currently underway. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|