Assessment of vascular inflammation and subclinical nephropathy in exaggerated blood pressure response to exercise test
| Autor: | Sinan Akıncı, Cihan Altin, Haldun Muderrisoglu, Gultekin Genctoy, Ali Çoner |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Vasculitis medicine.medical_specialty Blood Pressure Urine 030204 cardiovascular system & hematology Assessment and Diagnosis Nephropathy 03 medical and health sciences 0302 clinical medicine Internal medicine Heart rate Internal Medicine Medicine Humans 030212 general & internal medicine Risk factor Exercise Abdominal obesity Subclinical infection Aged Advanced and Specialized Nursing Inflammation business.industry General Medicine Blood Pressure Monitoring Ambulatory Middle Aged medicine.disease Healthy Volunteers Blood pressure C-Reactive Protein Obesity Abdominal Hypertension Cardiology Exercise Test Female Kidney Diseases medicine.symptom Cardiology and Cardiovascular Medicine business Kidney disease |
| Zdroj: | Blood pressure monitoring. 24(3) |
| ISSN: | 1473-5725 |
| Popis: | OBJECTIVES Exaggerated blood pressure response (EBPR) to exercise tests is an additional cardiovascular risk factor and predictor of future development of hypertension. However, there are conflicting data on the diagnostic threshold of EBPR and its clinical importance in kidney disease. The aim of this study was to investigate vascular inflammation and subclinical nephropathy in otherwise healthy volunteers with EBPR. PATIENTS AND METHODS The study included 170 middle-aged, healthy volunteers (mean age: 43.3±6.9; range: 35-65 years: 100 men and 70 women). Participants performed a treadmill exercise test until they reached their age-adjusted maximum heart rate and were divided into EBPR and normal/physiological blood pressure response groups. Before exercise tests, serum high sensitive C-reactive protein (hs-CRP) and urine albumin-to-creatinine ratio were measured to evaluate vascular inflammation and subclinical nephropathy, respectively. Anthropometrical measurements, fasting serum glucose, fasting lipid profile, and the full blood count of participants were also evaluated. RESULTS EBPR was detected in 31 (18.2%) participants. Hs-CRP levels (1.03 vs. 0.46 mg/l) (P |
| Databáze: | OpenAIRE |
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