Photochemically Induced Electron Transfer (PET) Catalyzed Radical Cyclization: A Practical Method for Inducing Structural Changes in Peptides by Formation of Cyclic Amino Acid Derivatives

Autor:	Marco Jonas, Eberhard Steckhan, Siegfried Blechert
Rok vydání:	2001
Předmět:	chemistry.chemical_classification Free Radicals Photochemistry Organic Chemistry Amino Acids Cyclic Electrons Combinatorial chemistry Radical cyclization Catalysis Amino acid Electron transfer chemistry Peptide chemistry Peptides
Zdroj:	The Journal of Organic Chemistry. 66:6896-6904
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo010144b
Popis:	A new radical cyclization reaction of unsaturated amino acid derivatives is presented. The reaction is induced by photoelectron transfer (PET) catalysis and proceeds, in comparison to commonly applied methods, under mild, nonoxidizing, and nontoxic conditions in neutral medium. This type of radical cyclization reaction can be used in peptide chemistry for inducing structural changes in peptides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4626750423419b91713d1d028d2b53 https://doi.org/10.1021/jo010144b Zobrazit plný text záznamu