A beat-by-beat cardiovascular index, CARDEAN, to titrate opioid administration in the setting of orthopaedic surgery: a prospective randomized trial
| Autor: | Benjamin Riche, Damien Loheas, Muriel Rabilloud, Marc Puidupin, Luc Quintin, Jacques Escarment, Antoine Lamblin, Pierre-François Wey, Jean-Yves Martinez, Andrei Cividjian |
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| Rok vydání: | 2020 |
| Předmět: |
Tachycardia
medicine.medical_specialty Sufentanil Blood Pressure Health Informatics Critical Care and Intensive Care Medicine law.invention Randomized controlled trial law Anesthesiology Heart rate medicine Humans Orthopedic Procedures Prospective Studies business.industry Hazard ratio Analgesics Opioid Anesthesiology and Pain Medicine Blood pressure Bispectral index Anesthesia medicine.symptom business medicine.drug |
| Zdroj: | Journal of Clinical Monitoring and Computing. 35:1311-1324 |
| ISSN: | 1573-2614 1387-1307 |
| DOI: | 10.1007/s10877-020-00597-6 |
| Popis: | To determine whether a beat-by-beat cardiovascular index (CARDEAN: cardiovascular depth of analgesia, Alpha-2 Ltd, Lyon, France) reduces the incidence of tachycardia in ASA I–III patients undergoing orthopaedic surgery. A total of 76 patients were prospectively randomized into (1) a control group or (2) the CARDEAN group, in which the nurse anaesthetist was blinded to CARDEAN application. In addition to conventional signs, an external observer instructed the nurse anaesthetist to administer sufentanil 0.1 µg kg−1 when the CARDEAN crossed a threshold (≥ 60). The primary outcome was the incidence of tachycardia (> 120% of reference heart rate, HR). Non-invasive blood pressure (BP), electrocardiogram (ECG), O2 saturation-photoplethysmography and the bispectral index (40 |
| Databáze: | OpenAIRE |
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