Plasmapheresis Effect on Hematological and Biochemical Parameters in Athletic Horses Subjected to Exercise
| Autor: | Jamal Chakir, Mohammed Ouassat, Réda Daden, Khalid El Allali, Mohamed Rachid Achaâban, Mohammed Piro, Fatima Zahraa Zarhouni |
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| Rok vydání: | 2019 |
| Předmět: |
040301 veterinary sciences
medicine.medical_treatment Hematocrit Body weight 0403 veterinary science White blood cell Physical Conditioning Animal medicine Animals Horses Creatine Kinase medicine.diagnostic_test Equine business.industry 0402 animal and dairy science Horse 04 agricultural and veterinary sciences Hematology Plasmapheresis 040201 dairy & animal science Red blood cell medicine.anatomical_structure Anesthesia Hemoglobin business Sports |
| Zdroj: | Journal of equine veterinary science. 81 |
| ISSN: | 0737-0806 |
| Popis: | To evaluate the effect of plasmapheresis on clinical, hematological, and biochemical parameters after exercise, a plasmapheresis session was realized on six jumping horses (plasmapheresis group) that underwent three consecutive days of physical graded exercise. The control group (n = 6) went through the same exercise but not subjected to the plasmapheresis session. Seventeen milliliters of plasma/kg of body weight was harvested from each horse. The procedure was well tolerated by the horses. The plasmapheresis leads to a significant increase of the hemoglobin, hematocrit, red blood cell, white blood cell, and lymphocytes counts. Plasmapheresis induced a very significant decrease (P.001) of albumin and globulin levels and of total protein, which were reestablished 24 hours later. Plasmapheresis also generated a very significant increase (P.001) in sodium levels and a significant decline of potassium (P.05) and calcium (P.01) levels. Several other biochemical variables remained unchanged. Results also showed that, after a significant rise of lactate, aspartate aminotransferase, and creatine kinase levels which are subsequent to the exercise, the plasmapheresis session induced a very significant continuous decrease (P.001) of these parameters. The present work has demonstrated that the plasmapheresis is able to modify the physiology after exercise and to affect both the hematology and the biochemistry of the blood hematobiochemical parameters in horses subjected to physical exercise. |
| Databáze: | OpenAIRE |
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