Synchronous or metachronous lymphoma and metastatic cutaneous squamous cell carcinoma in the head and neck region: a diagnostic and management dilemma
| Autor: | Brenton Wylie, S. Shashinder, B. Leavers, Imran Kader, K-K. Chi, Purnima Sundaresan |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Oncology medicine.medical_specialty Chronic lymphocytic leukemia Neoplasms Multiple Primary 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Internal medicine medicine Humans Combined Modality Therapy 030223 otorhinolaryngology Aged medicine.diagnostic_test business.industry Lymphoma Non-Hodgkin Head and neck cancer Cancer Neoplasms Second Primary General Medicine medicine.disease Lymphoma Otorhinolaryngology Head and Neck Neoplasms Positron emission tomography Positron-Emission Tomography 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Histopathology Radiology Skin cancer business |
| Zdroj: | The Journal of Laryngology & Otology. 130:S45-S49 |
| ISSN: | 1748-5460 0022-2151 |
| DOI: | 10.1017/s002221511600832x |
| Popis: | Objective:To review our experience of managing patients with a dual diagnosis of metastatic cutaneous squamous cell carcinoma in the head and neck region and low-grade non-Hodgkin lymphoma. The secondary aim was to evaluate the utility of 18F-fluorodeoxyglucose positron emission tomography during diagnosis.Methods:Patients diagnosed with metastatic cutaneous squamous cell carcinoma of the head and neck and low-grade non-Hodgkin lymphoma, in a five-year period, were identified. Patient, tumour and treatment characteristics were identified. 18F-fluorodeoxyglucose positron emission tomography imaging was reviewed and correlated with histopathology findings.Results:Eight patients were identified. There was a delay in diagnosis of metastatic squamous cell carcinoma in two patients. 18F-fluorodeoxyglucose positron emission tomography differentiated metastatic squamous cell carcinoma from low-grade non-Hodgkin lymphoma with a sensitivity of 88.2 per cent and a specificity of 94.7 per cent. In 38 per cent of patients, compromises in management had to be made.Conclusion:The management of metastatic squamous cell carcinoma can be challenging in patients with low-grade non-Hodgkin lymphoma. 18F-fluorodeoxyglucose positron emission tomography can be useful in the diagnosis of metastatic squamous cell carcinoma in patients with low-grade non-Hodgkin lymphoma. |
| Databáze: | OpenAIRE |
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