Transanal endorectal pull-through procedure versus transabdominal surgery for Hirschsprung disease
Autor: | Xue-Si Wu, Hua-Lei Cui, Qian-Yu Yang, Le-Wee Bi, Bei-Lei Yan |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Constipation Hirschsprung disease Operative Time incontinence/soiling Cochrane Library law.invention 03 medical and health sciences Postoperative Complications 0302 clinical medicine Randomized controlled trial law Humans Minimally Invasive Surgical Procedures Medicine 030212 general & internal medicine Digestive System Surgical Procedures Enterocolitis enterocolitis business.industry Incidence (epidemiology) Infant Newborn Infant transanal endorectal pull-through constipation General Medicine Odds ratio Length of Stay transabdominal approach Confidence interval Surgery Child Preschool 030220 oncology & carcinogenesis Meta-analysis medicine.symptom business Fecal Incontinence Systematic Review and Meta-Analysis Research Article |
Zdroj: | Medicine |
ISSN: | 1536-5964 0025-7974 |
DOI: | 10.1097/md.0000000000016777 |
Popis: | Objective: To analyze the clinical results of transanal endorectal pull-through (TERPT) and transabdominal approach (TAB) in the treatment of Hirschsprung disease. Methods: We searched all publications in the PubMed, MEDLINE, EMBASE, and Cochrane library databases between January 2003 and November 2018. The study included randomized controlled trials (RCTs) and observational clinical studies (OCSs), to compare the surgery duration, length of postoperative hospital stay, incidence of postoperative incontinence/soiling, constipation, and enterocolitis between the TERPT and TAB groups. Mantel-Haenszel method was used for continuous variables, the combined odds ratios (ORs) and 95% confidence intervals (CIs) for dichotomous variables were used. Results: In the 87 studies, we include 1 case of RCTs and 9 cases of OCSs. Including 392 cases of TERPT and 332 cases of TAB groups. TERPT has a short postoperative hospitalization [mean difference (MD) = −6.74 day; 95% CIs; −13.26 to −0.23; P = .04], and a low incidence of postoperative incontinence (ORs = 0.54; 95% CIs, 0.35–0.83; P = .006) and constipation (ORs = 0.50; 95% CIs, 0.28–0.90; P = .02). There was no difference in duration of surgery (MD = −30.59 min; 95% CIs, −98.01–36.83; P = .37) and incidence of postoperative enterocolitis (ORs = 0.78; 95% CIs, 0.53–1.17; P = .23). Conclusion: TERPT is superior to TAB in terms of hospitalization time, postoperative incontinence, and constipation. However, there are still a large number of RCTs to verify, and more trials are expected to be testified in the future. |
Databáze: | OpenAIRE |
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