Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards
| Autor: | Hiroko Shibata, Shoichi Shimizu, Yuichi Iwai, Kohzoh Imai, Tomohiko Koibuchi, Takeshi Fujii, Masato Suzuki, Mika Kogayu, Hiroshi Mae, Eisuke Adachi |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pediatrics Tuberculosis health care facilities manpower and services education Population Prevalence Interferon gamma release assay Health care Medicine Latent tuberculosis infection education.field_of_study Health care workers Multidisciplinary Latent tuberculosis business.industry Research Medical record Public health virus diseases Latent tuberculosis infection baseline screening bacterial infections and mycoses medicine.disease Family medicine Quantiferon-TB gold in tube business |
| Zdroj: | SpringerPlus |
| ISSN: | 2193-1801 |
| DOI: | 10.1186/2193-1801-2-440 |
| Popis: | Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan. |
| Databáze: | OpenAIRE |
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