Amplification of Emerging Viruses in a Bat Colony
| Autor: | Christian Drosten, Victor M. Corman, Rodrigo Melim Zerbinati, Florian Gloza-Rausch, Antje Seebens, Marcel A. Müller, Adriana Fumie Tateno, Tom Wegner, Jan Felix Drexler |
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| Rok vydání: | 2011 |
| Předmět: |
Disease reservoir
Epidemiology viruses Population Dynamics coronavirus lcsh:Medicine Myotis myotis Breeding medicine.disease_cause astrovirus fluids and secretions Chiroptera Germany Zoonoses Phylogeny Coronavirus 0303 health sciences education.field_of_study Reverse Transcriptase Polymerase Chain Reaction virus diseases adenovirus 3. Good health Infectious Diseases Virus Diseases RNA Viral Female Microbiology (medical) animal structures reservoir ecology Molecular Sequence Data Population bats Biology Virus Adenoviridae lcsh:Infectious and parasitic diseases Astrovirus 03 medical and health sciences medicine Animals RNA Viruses lcsh:RC109-216 education Disease Reservoirs 030304 developmental biology zoonotic risk assessment 030306 microbiology Host (biology) Research lcsh:R Sequence Analysis DNA biology.organism_classification Virology DNA Viral Astroviridae |
| Zdroj: | Emerging Infectious Diseases; Vol 17 Emerging Infectious Diseases, Vol 17, Iss 3, Pp 449-456 (2011) Emerging Infectious Diseases |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | Concentration and prevalence of coronaviruses and astroviruses increase when bats form maternity roosts and bear young. Bats host noteworthy viral pathogens, including coronaviruses, astroviruses, and adenoviruses. Knowledge on the ecology of reservoir-borne viruses is critical for preventive approaches against zoonotic epidemics. We studied a maternity colony of Myotis myotis bats in the attic of a private house in a suburban neighborhood in Rhineland-Palatinate, Germany, during 2008, 2009, and 2010. One coronavirus, 6 astroviruses, and 1 novel adenovirus were identified and monitored quantitatively. Strong and specific amplification of RNA viruses, but not of DNA viruses, occurred during colony formation and after parturition. The breeding success of the colony was significantly better in 2010 than in 2008, in spite of stronger amplification of coronaviruses and astroviruses in 2010, suggesting that these viruses had little pathogenic influence on bats. However, the general correlation of virus and bat population dynamics suggests that bats control infections similar to other mammals and that they may well experience epidemics of viruses under certain circumstances. |
| Databáze: | OpenAIRE |
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