Non-interventional cardiologists' perspectives on the role of pharmacogenomic testing in cardiovascular medicine
| Autor: | Robert L. Page, Christina L. Aquilante, Yardlee S. Kauffman, Kris Oreschak, Kimberly M. Deininger, Yee Ming Lee, Samuel G. Johnson |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Health Knowledge Attitudes Practice Attitude of Health Personnel education Cardiology Pharmacogenomic Testing 030105 genetics & heredity 03 medical and health sciences 0302 clinical medicine Cardiologists medicine Humans cardiovascular diseases Precision Medicine Intensive care medicine Pharmacology business.industry General Medicine Clinical Practice Pharmacogenetics 030220 oncology & carcinogenesis Pharmacogenomics Non interventional Clinical validity Molecular Medicine Female Personalized medicine business Qualitative research |
| Zdroj: | Personalized medicine. 16(2) |
| ISSN: | 1744-828X |
| Popis: | Aim: To evaluate factors influencing cardiologists’ perspectives about pharmacogenomic (PGx) testing in clinical practice. Patients & methods: Semistructured interviews with practicing cardiologists were qualitatively analyzed to identify common themes. Results: Five themes were identified among 16 cardiologists from four specialties (n = 5 general cardiology, n = 3 electrophysiology, n = 2 adult congenital and n = 6 heart failure/transplant): cardiologists’ knowledge and needs, perceived clinical validity and utility of PGx testing, dissemination and management of PGx results, patient-related considerations and incidental findings. Conclusion: Lack of evidence was considered by many cardiologists to be a major barrier hindering the use of PGx testing. However, they would consider adopting PGx if they were provided additional education, ongoing support and evidence supporting the clinical utility of PGx testing in cardiovascular medicine. |
| Databáze: | OpenAIRE |
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