Necrotizing Skin and Soft Tissue Infections Admitted to Intensive Care Unit in Reunion Island: A Retrospective Cohort Study

Autor: Alexia Mubuanga Nkusu, Bernard-Alex Gaüzère, Olivier Martinet, David Vandroux
Přispěvatelé: Neuroépidémiologie Tropicale (NET), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Centre de Médecine Tropicale René Labusquière, Service d'Anesthésie-Réanimation [CHU Limoges], CHU Limoges, Centre hospitalier Félix-Guyon [Saint-Denis, La Réunion]
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
medicine.medical_treatment
Comorbidity
law.invention
0302 clinical medicine
Risk Factors
law
Vasoconstrictor Agents
Hospital Mortality
030212 general & internal medicine
Skin Diseases
Infectious
Mortality rate
Incidence (epidemiology)
Anti-Inflammatory Agents
Non-Steroidal
Soft tissue
Articles
Middle Aged
Staphylococcal Infections
Shock
Septic
Intensive care unit
3. Good health
Renal Replacement Therapy
Intensive Care Units
Infectious Diseases
medicine.anatomical_structure
Hypertension
Female
Staphylococcus aureus
medicine.medical_specialty
Streptococcus pyogenes
030231 tropical medicine
Amputation
Surgical
Necrosis
03 medical and health sciences
Streptococcal Infections
Virology
Internal medicine
Diabetes Mellitus
medicine
Humans
Hypoglycemic Agents
Fasciitis
Necrotizing
Renal Insufficiency
Chronic
Aged
Retrospective Studies
Arteritis
Debridement
business.industry
Soft Tissue Infections
Streptococcus
Retrospective cohort study
Respiration
Artificial
Perineum
Amputation
Fluid Therapy
Parasitology
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Gram-Negative Bacterial Infections
business
Reunion
Zdroj: American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2021, 105 (3), pp.596-599. ⟨10.4269/ajtmh.21-0009⟩
Am J Trop Med Hyg
ISSN: 0002-9637
DOI: 10.4269/ajtmh.21-0009⟩
Popis: This retrospective and single-center study in Reunion Island (Indian Ocean) assessed frequency, mortality, causative pathogens of severe necrotizing skin, and necrotizing skin and soft tissue infections (NSSTIs) admitted in intensive care unit (ICU). Sixty-seven consecutive patients were included from January 2012 to December 2018. Necrotizing skin and soft tissue infection represented 1.06% of total ICU admissions. We estimate the incidence of NSSTI requiring ICU at 1.21/100,000 person/years in Reunion Island. Twenty (30%) patients were receiving nonsteroidal anti-inflammatory drugs (NSAIDs) prior to admission in ICU and 40 (60%) were diagnosed patients with diabetes. Sites of infection were the lower limb in 52 (78%) patients, upper limb in 4 (6%), and perineum in 10 (15%). The surgical treatment was debridement for 40 patients, whereas 11 patients required an amputation. The most commonly isolated microorganisms were Streptococci (42%) and Gram-negative bacteria (22%).The mortality rate was 25.4%. NSAIDs did not influence mortality when interrupted upon admission to ICU.
Databáze: OpenAIRE
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