Direct demonstration of the effects of repetitive transcranial magnetic stimulation on the excitability of the human motor cortex
| Autor: | V. Di Lazzaro, Alfredo Berardelli, Angelo Insola, P. Tonali, Jc Rothwell, E. Saturno, Antonio Oliviero, Paolo Mazzone, Fabio Pilato, Michele Dileone |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Neurology medicine.medical_treatment Central nervous system Neural Conduction Pyramidal Tracts behavioral disciplines and activities medicine Humans Aged Pyramidal tracts business.industry General Neuroscience Motor Cortex Middle Aged Evoked Potentials Motor Transcranial Magnetic Stimulation Electric Stimulation Intensity (physics) Transcranial magnetic stimulation Electrophysiology medicine.anatomical_structure business Neuroscience Motor cortex |
| Zdroj: | Experimental Brain Research. 144:549-553 |
| ISSN: | 1432-1106 0014-4819 |
| DOI: | 10.1007/s00221-002-1106-9 |
| Popis: | The effects of repetitive transcranial magnetic stimulation (rTMS; 20 stimuli at 5 Hz at 120% resting motor threshold intensity using a biphasic stimulus pulse) on the excitability of human motor cortex were investigated in two patients who had an electrode implanted into the cervical epidural space. The corticospinal D wave increased in amplitude with successive stimuli, and reached a maximum after three or five pulses. At this stage, the amplitude of the I waves was unchanged, but after a further 10 stimuli an additional I wave was recruited. Both effects were still evident 2 min after the end of the rTMS. The effects are compatible with a short-term increase in cortical excitability during suprathreshold rTMS. |
| Databáze: | OpenAIRE |
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