Microvascular clamp technique as a reversible simulation of parathyroid gland excision
| Autor: | Garth Olson, Nathan Boyd, Noah Syme, Michael F. Spafford |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adenoma
medicine.medical_specialty Urology Parathyroid hormone Cohort Studies 03 medical and health sciences 0302 clinical medicine medicine Humans Parathyroid adenoma Retrospective Studies Parathyroidectomy Intraoperative Care Vascular pedicle business.industry Retrospective cohort study General Medicine medicine.disease Constriction Clamp medicine.anatomical_structure Parathyroid Neoplasms Tissue ischemia Parathyroid Hormone 030220 oncology & carcinogenesis Microvessels Parathyroid adenoma excision 030211 gastroenterology & hepatology Surgery Parathyroid gland business |
| Zdroj: | American journal of surgery. 219(6) |
| ISSN: | 1879-1883 |
| Popis: | Introduction This study demonstrates the effectiveness of a microvascular clamp to simulate parathyroid adenoma excision with respect to intraoperative parathyroid hormone (ioPTH) changes in vivo. Methods Cases in which microvascular clamps were employed intraoperatively in conjunction with intraoperative parathyroid hormone(ioPTH) assays were reviewed. ioPTH values were recorded throughout these procedures to assess the efficacy and reversibility of tissue ischemia using microvascular clamps. Results Application of a microvascular clamp across the vascular pedicle of a parathyroid adenoma resulted in a significant ioPTH drop in 95% of cases (N = 20). Removal of the clamp resulted in complete or partial rebound of ioPTH in 90% of cases (N = 20). Conclusion The use of a microvascular clamp to temporarily occlude a parathyroid gland’s vascular pedicle is an effective simulation of gland excision with respect to ioPTH changes. Rebound of ioPTH levels after clamp removal demonstrates that this technique is generally reversible. Level of evidence 2b, Retrospective cohort study. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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