Hypothyroidism in Pregnancy
Autor: | Peter N. Taylor, John H. Lazarus |
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Rok vydání: | 2019 |
Předmět: |
Thyroid Hormones
endocrine system medicine.medical_specialty endocrine system diseases Thyroid screening Hormone Replacement Therapy Offspring Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Endocrinology Hypothyroidism Pregnancy Prenatal Diagnosis Humans Mass Screening Medicine Fetus business.industry Obstetrics Thyroid medicine.disease Hypothalamic–pituitary–thyroid axis Pregnancy Complications medicine.anatomical_structure 030220 oncology & carcinogenesis Practice Guidelines as Topic Female Thyroid function business Hormone |
Zdroj: | Endocrinology and Metabolism Clinics of North America. 48:547-556 |
ISSN: | 0889-8529 |
DOI: | 10.1016/j.ecl.2019.05.010 |
Popis: | Thyroid hormone is essential for pregnancy and ensuring fetal development. Pregnancy also places substantial demands on the thyroid axis. Overt hypothyroidism is associated with substantial adverse obstetric and offspring outcomes and requires treatment. Borderline thyroid dysfunction is common in women and associated with adverse obstetric and offspring outcomes, although benefits of screening for and treating borderline thyroid function are unclear. Many women are established on thyroid hormone replacement before pregnancy and doses need increasing during pregnancy. Care is taken to prevent overreplacement. Universal thyroid screening in pregnancy is being undertaken in several countries, although it remains a matter of debate. |
Databáze: | OpenAIRE |
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