Acute on chronic liver failure
| Autor: | Angels Escorsell Mañosa, Antoni Mas Ordeig |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Liver Cirrhosis
medicine.medical_specialty Hepatorenal Syndrome Time Factors Multiple Organ Failure medicine.medical_treatment Economic shortage Liver transplantation Liver disease Hepatorenal syndrome Actuarial Analysis Humans Medicine Acute on chronic liver failure Intensive care medicine Hepatic encephalopathy Hepatology business.industry Liver Diseases Advanced cirrhosis Incidence (epidemiology) Gastroenterology Liver Failure Acute medicine.disease Liver Transplantation Surgery Europe Hepatic Encephalopathy business Dialysis Liver Failure |
| Zdroj: | Gastroenterología y Hepatología. 33:126-134 |
| ISSN: | 0210-5705 |
| DOI: | 10.1016/j.gastrohep.2009.10.003 |
| Popis: | Acute-on-Chronic Liver Failure (ACLF) is a recently introduced term defined as severe acute deterioration of an established liver disease. This entity usually develops after an acute insult. The main clinical manifestations are hepatorenal syndrome, hepatic encephalopathy and organ failure, with a high risk of death in the short term. The true incidence of ACLF remains difficult to determine due to confusions surrounding the definition of this entity, but seems to be 40% at 5 years in patients with advanced cirrhosis, which translates into 4,000 cases in Europe within this time span. The treatment of choice is liver transplantation. However, due to the shortage of suitable organs and morbidity and mortality in these patients, other options must be used. |
| Databáze: | OpenAIRE |
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