Consensus meeting: monosodium glutamate – an update
Autor: | J D Fernstrom, Konrad Beyreuther, U Heinemann, R Walker, O Kempski, Hans Steinhart, W P Hammes, Hans Konrad Biesalski, Peter Stehle, Peter Grimm |
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Rok vydání: | 2006 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Monosodium glutamate Population Medicine (miscellaneous) Physiology chemistry.chemical_compound Bolus (medicine) Elderly persons Pregnancy Internal medicine Sodium Glutamate medicine Humans Palatability Child education Aged Aged 80 and over education.field_of_study Nutrition and Dietetics Dose-Response Relationship Drug Appetite Regulation business.industry Infant Newborn Glutamate receptor Infant Middle Aged Food safety Flavoring Agents Human nutrition Endocrinology chemistry Blood-Brain Barrier Consumer Product Safety Child Preschool Prenatal Exposure Delayed Effects Female Food Additives business |
Zdroj: | European Journal of Clinical Nutrition. 61:304-313 |
ISSN: | 1476-5640 0954-3007 |
DOI: | 10.1038/sj.ejcn.1602526 |
Popis: | Update of the Hohenheim consensus on monosodium glutamate from 1997: Summary and evaluation of recent knowledge with respect to physiology and safety of monosodium glutamate.Experts from a range of relevant disciplines received and considered a series of questions related to aspects of the topic.University of Hohenheim, Stuttgart, Germany.The experts met and discussed the questions and arrived at a consensus.Total intake of glutamate from food in European countries is generally stable and ranged from 5 to 12 g/day (free: ca. 1 g, protein-bound: ca. 10 g, added as flavor: ca. 0.4 g). L-Glutamate (GLU) from all sources is mainly used as energy fuel in enterocytes. A maximum intake of 6.000 [corrected] mg/kg body weight is regarded as safe. The general use of glutamate salts (monosodium-L-glutamate and others) as food additive can, thus, be regarded as harmless for the whole population. Even in unphysiologically high doses GLU will not trespass into fetal circulation. Further research work should, however, be done concerning the effects of high doses of a bolus supply at presence of an impaired blood brain barrier function. In situations with decreased appetite (e.g., elderly persons) palatability can be improved by low dose use of monosodium-L-glutamate. |
Databáze: | OpenAIRE |
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