A colorimetric iron sensor based on the partition of phenanthroline complexes into polymeric hydrogels. Combinatorial synthesis and high throughput screening of the hydrogel matrix

Autor: Maria C. Miras, María Victoria Martinez, Claudia R. Rivarola, Cesar Alberto Barbero
Rok vydání: 2017
Předmět:
Físico-Química
Ciencia de los Polímeros
Electroquímica
Phenanthroline
Radical polymerization
Analytical chemistry
02 engineering and technology
010402 general chemistry
01 natural sciences
chemistry.chemical_compound
Spectrophotometry
Materials Chemistry
medicine
Electrical and Electronic Engineering
Instrumentation
Detection limit
medicine.diagnostic_test
HYDROGEL
IRON
Ciencias Químicas
technology
industry
and agriculture
Metals and Alloys
SENSOR
WATER QUALITY
021001 nanoscience & nanotechnology
Condensed Matter Physics
0104 chemical sciences
Surfaces
Coatings and Films
Electronic
Optical and Magnetic Materials
COLORIMETRIC
Partition coefficient
Monomer
chemistry
Acrylamide
Self-healing hydrogels
LIGANDS
0210 nano-technology
COMBINATORIAL CHEMISTRY
CIENCIAS NATURALES Y EXACTAS
Nuclear chemistry
Zdroj: Sensors and Actuators B: Chemical. 241:19-32
ISSN: 0925-4005
DOI: 10.1016/j.snb.2016.10.013
Popis: A combinatorial library of hydrogels is produced by radical polymerization and tested for retention of iron (II) complexes, using a simple colorimetric high throughput screening (HTS). Six acrylamide monomers are used to produce a library of 21 cross-linked hydrogel matrixes. The swelling of all hydrogels is determined and related with the structure of each monomer unit present. The HTS shows that some materials are able to retain the tris(phenanthroline)iron(II) (Fe(Phen)32+) complex. The partition coefficient of Fe(H2O)62+ and Fe(Phen)32+ in all hydrogels is determined by UV–vis spectrophotometry and related with the presence of anionic (e.g. −SO3−), hydrophobic (e.g. isopropyl) and hydrophilic (e.g. −NH2 of acrylamide) groups. Hydrogels with sulfonic (−SO3−) groups show large values of partition coefficients of Fe2+ into the hydrogel (>500). Based on the data and HTS, poly(acrylamide-co-50%(2-acrylamido-2-methylpropansulfonic acid)) (PAAm-co-50%AMPS) is selected to build a colorimetric sensor. Since the phenanthroline could be released from the hydrogel, bathophenanthroline (BPhen) which is not released is used as ligand. The hydrogel is loaded with BPhen and exposed to Fe2+ in water. The visual detection of color gives a detection limit of 0.1 ppm. Little interference of different common ions is found. A special set-up is made which allows spectrophotometric measurement of the complex inside the gel. The detection limit is found to be of ca. 0.01 ppm by spectrophotometry. Using the sensor, the iron content in milk is measured directly demonstrating the use of the sensor to measure free iron in opaque liquids where solution spectrophotometry is not effective without complex sample pretreatments. The non-covalent retention of ligands and complexes inside polymeric hydrogels seems to be a suitable method for building specific ion sensors. Fil: Martínez, María Victoria. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina Fil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina Fil: Miras, María Cristina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina Fil: Barbero, César Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Databáze: OpenAIRE
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