Plasticity in the barrel cortex of the adult mouse: transient increase of GAD-immunoreactivity following sensory stimulation
| Autor: | Egbert Welker, H. Van der Loos, Josef Dörfl, Eduardo Soriano |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Neuronal Plasticity
Sensory stimulation therapy Glutamate Decarboxylase General Neuroscience Glutamate decarboxylase Stimulation Sensory system Somatosensory Cortex Barrel cortex Biology Somatosensory system Immunohistochemistry Mice Physical Stimulation Vibrissae Neuroplasticity Animals Sensory deprivation Mechanoreceptors Neuroscience |
| Zdroj: | Experimental Brain Research. 78:659-664 |
| ISSN: | 1432-1106 0014-4819 |
| Popis: | Sensory experience during perinatal life and adulthood modifies physiological and anatomical characteristics of the central nervous system. So far, this phenomenon has been studied in situations of complete or partial sensory deprivation. We here report that increased sensory stimulation, during four days, of a number of whisker follicles on the face of the adult mouse results in an increased immunoreactivity of glutamic acid decarboxylase (the biosynthetic enzyme of the inhibitory neurotransmitter GABA) in the somatosensory cortex of the adult mouse. Effects were limited to a column of tissue corresponding to the representation of the stimulated follicles and lasted two days beyond stimulation. These findings suggest that sensory stimulation transiently modifies local cortical processing. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink