Alveolar echinococcosis in a dog in the eastern United States
| Autor: | Andrew S. Peregrine, Emily J. Jenkins, Bethany St John, Donald Fairman, Bridgette Wells, Anne M. Zajac, Evan McGee, Tanya LeRoith |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Echinococcosis Hepatic Pathology medicine.medical_specialty 040301 veterinary sciences Alveolar echinococcosis Physical examination Brief Communication Albendazole Echinococcus multilocularis 030308 mycology & parasitology 0403 veterinary science 03 medical and health sciences Lethargy Dogs Fatal Outcome Small animal medicine Animals Dog Diseases 0303 health sciences General Veterinary medicine.diagnostic_test biology business.industry Virginia Anticestodal Agents 04 agricultural and veterinary sciences biology.organism_classification Labrador Retriever business |
| Zdroj: | J Vet Diagn Invest |
| ISSN: | 1943-4936 1040-6387 |
| Popis: | An 8-y-old Labrador Retriever was presented to a small animal practice in northern Virginia with a history of recent lethargy. Physical examination findings were unremarkable. Ultrasound revealed several large hepatic masses and multiple smaller masses involving the pancreas. Cytologic findings on fine-needle aspirates of the hepatic masses included inflammation and necrosis with eosinophilic, membranous oval structures consistent with cestode infection. Histopathologic findings for biopsies of these masses included extensive necrosis, inflammation, and PAS-positive hyaline-like membranous material interpreted as metacestode cyst wall. A PCR product was generated from aspirate material using primers specific for Echinococcus multilocularis. Subsequent sequence data were 100% homologous to E. multilocularis NADH dehydrogenase subunit I gene sequences. The dog received daily oral albendazole (10 mg/kg) treatment, but its condition deteriorated, and the dog was euthanized. The dog, born in Mississippi, was brought as a puppy to Virginia with no other travel history. To our knowledge, alveolar echinococcosis has not been reported previously in a dog in the United States; E. multilocularis infection was apparently acquired in the mid-Atlantic region of the United States. |
| Databáze: | OpenAIRE |
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